SCHEMBL9250480

SCHEMBL9250480

O=C(O)c1cc2cc(I)ccc2c(I)c1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 2/20 0.44
GRIN2A Q12879 2/20 0.44
GRIN2B Q13224 2/20 0.44
GRIN2C Q14957 2/20 0.44
POLB P06746 1/20 0.41
GPR35 Q9HC97 1/20 0.41
TP53 P04637 1/20 0.41
HPGD P15428 2/20 0.40
HSD17B10 Q99714 2/20 0.40
CYP2D6 P10635 1/20 0.40
THRB P10828 1/20 0.40
CYP2C9 P11712 1/20 0.40
TSHR P16473 1/20 0.40
ALOX12 P18054 1/20 0.40
ATIC P31939 1/20 0.40
PTPRC P08575 1/20 0.39
PTPN2 P17706 1/20 0.39
PTPN1 P18031 1/20 0.39
PTPRA P18433 1/20 0.39
PTPRB P23467 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL569239 0.83 GRIN2A (0.49) GRIN2DGRIN2AGRIN2BGRIN2CPOLB
SCHEMBL569862 0.81 GRIN2D (0.69) GRIN2DGRIN2AGRIN2BGRIN2CPOLB
SCHEMBL569680 0.81 POLB (0.63) GRIN2DGRIN2AGRIN2BGRIN2CPOLB
SCHEMBL6883218 0.71 PTPN1 (0.66) GRIN2DGRIN2AGRIN2BGRIN2CHPGD
SCHEMBL25979871 0.68 AKR1C2 (0.46) TP53HPGDHSD17B10THRBCYP2C9
SCHEMBL6423930 0.68 PTPN1 (0.56) GRIN2DGRIN2AGRIN2BGRIN2CPOLB
SCHEMBL31491424 0.67 TP53 (0.58) TP53HPGDHSD17B10THRBCYP2C9
SCHEMBL29662013 0.67 CA1 (0.61) HPGDHSD17B10THRBCYP2C9PTPRC
SCHEMBL980376 0.67 ALDH1A1 (0.61) POLBHPGDHSD17B10CYP2C9TSHR
SCHEMBL129664 0.67 CA1 (0.61) HPGDHSD17B10THRBCYP2C9PTPRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5451482-A Toner compositions with hydroxy naphthoic acid charge enhancing additives XEROX CORPORATION (US) 1995-09-19 US claimed
US-5451482-A Toner compositions with hydroxy naphthoic acid charge enhancing additives XEROX CORPORATION (US) 1995-09-19 US disclosed