SCHEMBL925058

SCHEMBL925058

CC(C)(c1ccccc1)c1cc(Cc2cc(C(C)(C)c3ccccc3)cc(C(C)(C)c3ccccc3)c2O)c(O)c(C(C)(C)c2ccccc2)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.47
ESR2 Q92731 4/20 0.47
CYP3A4 P08684 4/20 0.47
ALDH1A1 P00352 2/20 0.47
CNR1 P21554 4/20 0.43
CNR2 P34972 4/20 0.43
HSPA5 P11021 2/20 0.42
ALOX15 P16050 2/20 0.42
MAPK1 P28482 1/20 0.42
HTT P42858 1/20 0.42
CYP2C9 P11712 3/20 0.41
CYP2C19 P33261 3/20 0.41
HIF1A Q16665 3/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
NR3C2 P08235 1/20 0.39
KLF10 Q13118 1/20 0.39
HSD17B10 Q99714 3/20 0.37
CYP2D6 P10635 2/20 0.37
TSHR P16473 3/20 0.37
CYP1A2 P05177 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18969699 0.89 KLF10 (0.49) ESR1ESR2CYP3A4ALDH1A1CNR1
SCHEMBL11294193 0.87 CYP3A4 (0.44) ESR1ESR2CYP3A4ALDH1A1CNR1
SCHEMBL14705550 0.87 ESR1 (0.44) ESR1ESR2CYP3A4ALDH1A1CNR1
SCHEMBL18511698 0.87 ESR1 (0.44) ESR1ESR2CYP3A4ALDH1A1CNR1
SCHEMBL1276281 0.86 ESR1 (0.57) ESR1ESR2CYP3A4ALDH1A1CNR1
SCHEMBL11212278 0.85 HSPA5 (0.62) ESR1ESR2CYP3A4ALDH1A1CNR1
SCHEMBL18969673 0.84 ESR1 (0.46) ESR1ESR2CYP3A4ALDH1A1CNR1
SCHEMBL27949954 0.84 CYP3A4 (0.42) ESR1ESR2CYP3A4ALDH1A1CNR1
SCHEMBL25037486 0.82 ALOX15 (0.50) ESR1ESR2CYP3A4ALDH1A1CNR1
SCHEMBL1262470 0.81 ALDH1A1 (0.52) ESR1ESR2CYP3A4ALDH1A1CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9839906-B1 Catalyst and method for synthesizing cyclic carbonate by the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2017-12-12 US disclosed
EP-2445920-B1 PHOSPHITE CONTAINING CATALYSTS FOR HYDROFORMYLATION PROCESSES EASTMAN CHEM CO (US) 2014-03-19 EP disclosed
EP-2445920-A1 PHOSPHITE CONTAINING CATALYSTS FOR HYDROFORMYLATION PROCESSES Eastman Chemical Company (US) 2012-05-02 EP disclosed
EP-2240275-B1 FLUOROPHOSPHITE CONTAINING CATALYSTS FOR HYDROFORMYLATION PROCESSES EASTMAN CHEM CO (US) 2011-11-23 EP disclosed
US-7928267-B1 Phosphite containing catalysts for hydroformylation processes EASTMAN CHEMICAL COMPANY (US) 2011-04-19 US disclosed
US-7872156-B2 Fluorophosphite containing catalysts for hydroformylation processes EASTMAN CHEMICAL COMPANY (US) 2011-01-18 US disclosed
US-7872157-B2 Phosphonite containing catalysts for hydroformylation processes EASTMAN CHEMICAL COMPANY (US) 2011-01-18 US disclosed
WO-2010151285-A1 PHOSPHITE CONTAINING CATALYSTS FOR HYDROFORMYLATION PROCESSES EASTMAN CHEMICAL COMPANY (US) 2010-12-29 WO disclosed
EP-2240275-A1 FLUOROPHOSPHITE CONTAINING CATALYSTS FOR HYDROFORMYLATION PROCESSES Eastman Chemical Company (US) 2010-10-20 EP disclosed
EP-2231330-A1 PHOSPHONITE CONTAINING CATALYSTS FOR HYDROFORMYLATION PROCESSES Eastman Chemical Company (US) 2010-09-29 EP disclosed
WO-2009085161-A1 PHOSPHONITE CONTAINING CATALYSTS FOR HYDROFORMYLATION PROCESSES EASTMAN CHEMICAL COMPANY (US) 2009-07-09 WO disclosed
WO-2009085160-A1 FLUOROPHOSPHITE CONTAINING CATALYSTS FOR HYDROFORMYLATION PROCESSES EASTMAN CHEMICAL COMPANY (US) 2009-07-09 WO disclosed
US-20090171122-A1 PHOSPHONITE CONTAINING CATALYSTS FOR HYDROFORMYLATION PROCESSES EASTMAN CHEMICAL COMPANY (US) 2009-07-02 US disclosed
US-20090171121-A1 FLUOROPHOSPHITE CONTAINING CATALYSTS FOR HYDROFORMYLATION PROCESSES EASTMAN CHEMICAL COMPANY (US) 2009-07-02 US disclosed
EP-0003338-B1 USE OF BENZYL-PHENOLS AS ANTIOXIDANTS BAYER AG (DE) 1983-03-09 EP disclosed
EP-0003338-A2 Use of benzyl-phenols as antioxidants BAYER AG (DE) 1979-08-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090171122-A1 PHOSPHONITE CONTAINING CATALYSTS FOR HYDROFORMYLATION PROCESSES GRK1, PHOSPHO1, GRIA1 ESR1 345/4885ESR2 164/4885CYP3A4 1633/4885
US-20090171121-A1 FLUOROPHOSPHITE CONTAINING CATALYSTS FOR HYDROFORMYLATION PROCESSES HRH3, EEF1A1, ARL1 ESR1 118/4885ESR2 55/4885CYP3A4 460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.