Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.38 |
| ▸ | F10 | P00742 | 5/20 | 0.38 |
| ▸ | F2 | P00734 | 4/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.38 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.33 |
| ▸ | ADH5 | P11766 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | F9 | P00740 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9256201 | 0.88 | TMPRSS15 (0.35) | ITGB3ITGA2BF10F2PRSS1 | |
| SCHEMBL9247247 | 0.86 | ITGB3 (0.37) | ITGB3ITGA2BF10F2PRSS1 | |
| SCHEMBL9255393 | 0.84 | ITGB3 (0.38) | ITGB3ITGA2BF10F2PRSS1 | |
| SCHEMBL9257847 | 0.83 | ITGB3 (0.49) | ITGB3ITGA2BF10F2PRSS1 | |
| SCHEMBL9247108 | 0.83 | ITGB3 (0.35) | ITGB3ITGA2BF10F2PRSS1 | |
| SCHEMBL9257511 | 0.81 | ITGB3 (0.41) | ITGB3ITGA2BF10F2PRSS1 | |
| SCHEMBL9256993 | 0.80 | ITGB3 (0.40) | ITGB3ITGA2BF10F2PRSS1 | |
| SCHEMBL9568440 | 0.76 | ITGB3 (0.39) | ITGB3ITGA2BF10F2PRSS1 | |
| SCHEMBL9252503 | 0.75 | TMPRSS15 (0.35) | ITGB3ITGA2BF10F2PRSS1 | |
| SCHEMBL9254757 | 0.75 | ITGB3 (0.36) | ITGB3ITGA2BF10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |