Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253978 | 0.94 | ITGB3 (0.37) | ITGB3ITGA2BPDK1F10PRSS1 | |
| SCHEMBL8863938 | 0.88 | TMPRSS15 (0.36) | ITGB3ITGA2BPDK1F10PRSS1 | |
| SCHEMBL9250967 | 0.87 | MAP4K4 (0.41) | ITGB3ITGA2BF10PRSS1F2 | |
| SCHEMBL9251800 | 0.87 | PDK1 (0.36) | PDK1 | |
| SCHEMBL9254094 | 0.86 | F2 (0.37) | ITGB3ITGA2BPDK1F10PRSS1 | |
| SCHEMBL9256993 | 0.85 | ITGB3 (0.40) | ITGB3ITGA2BF10PRSS1F2 | |
| SCHEMBL9254462 | 0.85 | PDK1 (0.38) | PDK1MAP4K4 | |
| SCHEMBL9250512 | 0.84 | POLB (0.36) | PDK1F10PRSS1F2MAP4K4 | |
| SCHEMBL9253138 | 0.84 | F10 (0.32) | PDK1F10PRSS1F2MAP4K4 | |
| SCHEMBL9257720 | 0.84 | ITGB3 (0.33) | ITGB3ITGA2BPDK1F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | claimed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |