Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 4/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.36 |
| ▸ | PLG | P00747 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | C1S | P09871 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9256770 | 0.87 | ITGB3 (0.35) | NQO2ITGB3ITGA2BPLGF2 | |
| SCHEMBL9259804 | 0.79 | MMP2 (0.44) | NQO2 | |
| SCHEMBL9253132 | 0.78 | ITGB3 (0.51) | NQO2ITGB3ITGA2BPLGF2 | |
| SCHEMBL9256974 | 0.78 | ITGB3 (0.51) | NQO2ITGB3ITGA2BPLGF2 | |
| SCHEMBL9255915 | 0.77 | ITGB3 (0.44) | NQO2ITGB3ITGA2BF2PRSS1 | |
| SCHEMBL9254922 | 0.77 | GRK6 (0.42) | NQO2ITGB3ITGA2BWDR5 | |
| SCHEMBL9254458 | 0.77 | ITGB3 (0.52) | ITGB3ITGA2BPLGPRSS1PLAU | |
| SCHEMBL9259655 | 0.76 | ITGB3 (0.46) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| SCHEMBL9259667 | 0.76 | ITGB3 (0.39) | NQO2ITGB3ITGA2BPLAU | |
| SCHEMBL9250640 | 0.74 | NQO2 (0.39) | NQO2ITGB3ITGA2BF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |