Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 2/20 | 0.36 |
| ▸ | DDO | Q99489 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851537 | 0.84 | FEN1 (0.49) | FEN1FFAR1GPR84HTR2ADAO | |
| SCHEMBL12836459 | 0.80 | FEN1 (0.52) | FEN1FFAR1GPR84HTR2ADAO | |
| Butyric Acid SCHEMBL9251506 | 0.79 | SMN1; SMN2 (0.40) | FEN1ALDH1A1TUBB4ATUBBTUBA3C | |
| SCHEMBL9128769 | 0.77 | FEN1 (0.50) | FEN1FFAR1GPR84HTR2ADAO | |
| SCHEMBL1071125 | 0.74 | GPR84 (0.44) | GPR84HTR2ADAO | |
| SCHEMBL28016595 | 0.74 | CNR1 (0.50) | FEN1FFAR1GPR84PARP1CNR1 | |
| SCHEMBL6035404 | 0.73 | GPR84 (0.42) | GPR84HTR2ADAO | |
| SCHEMBL29879228 | 0.71 | IMPDH2 (0.59) | FEN1PARP1PDE7ANPC1ALDH1A1 | |
| SCHEMBL12836461 | 0.71 | IMPDH2 (0.59) | FEN1PARP1PDE7ANPC1ALDH1A1 | |
| SCHEMBL7041118 | 0.69 | KDM4E (0.50) | FEN1DAODDOPARP1TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118459388-A | Indole benzoquinone derivative and preparation method and application thereof | 四川大学 | 2024-08-09 | — | — | CN | claimed |
| US-20250354108-A1 | METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS | UNIV DANMARKS TEKNISKE (DK) | 2025-11-20 | — | — | US | disclosed |
| EP-4526426-A2 | METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS | Danmarks Tekniske Universitet (DK) | 2025-03-26 | — | — | EP | disclosed |
| CN-118459388-B | Indole benzoquinone derivative and preparation method and application thereof | 四川大学 | 2024-09-03 | — | — | CN | disclosed |
| CN-118459388-A | Indole benzoquinone derivative and preparation method and application thereof | 四川大学 | 2024-08-09 | — | — | CN | disclosed |
| US-20240150313-A1 | TRI-SUBSTITUTED INDOLE BINDING FUNCTION 3 (BF3) COMPOUNDS AND METHODS FOR THEIR USE | UNIV BRITISH COLUMBIA (CA) | 2024-05-09 | — | — | US | disclosed |
| EP-4323372-A1 | TRI-SUBSTITUTED INDOLE BINDING FUNCTION 3 (BF3) COMPOUNDS AND METHODS FOR THEIR USE | The University Of British Columbia (CA) | 2024-02-21 | — | — | EP | disclosed |
| WO-2023222879-A2 | METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS | DANMARKS TEKNISKE UNIVERSITET (DK) | 2023-11-23 | — | — | WO | disclosed |
| CN-112041300-B | Indole and benzimidazole derivatives as dual 5-HT2A and 5-HT6 receptor antagonists | 阿达梅德制药公司 | 2023-07-28 | — | — | CN | disclosed |
| WO-2022219541-A1 | TRI-SUBSTITUTED INDOLE BINDING FUNCTION 3 (BF3) COMPOUNDS AND METHODS FOR THEIR USE | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2022-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240150313-A1 | TRI-SUBSTITUTED INDOLE BINDING FUNCTION 3 (BF3) COMPOUNDS AND METHODS FOR THEIR USE | KLK3, BRDT, HTR3A | FEN1 512/4885FFAR1 1378/4885GPR84 1866/4885 |
| US-20250354108-A1 | METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS | INMT, KARS1, MIA3 | FEN1 1031/4885FFAR1 1970/4885GPR84 3005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.