Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 3/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | P4HB | P07237 | 8/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16619152 | 0.79 | PDCD1 (0.50) | FBP1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL27336648 | 0.78 | GRIN2D (0.50) | FBP1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7331821 | 0.76 | PDCD1 (0.48) | FBP1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3208694 | 0.76 | FBP1 (0.49) | FBP1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL8668592 | 0.75 | FBP1 (0.45) | FBP1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL29463498 | 0.75 | FBP1 (0.56) | FBP1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3216977 | 0.75 | FBP1 (0.51) | FBP1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL67236 | 0.75 | FBP1 (0.56) | FBP1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL2774364 | 0.74 | FBP1 (0.65) | FBP1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1687910 | 0.74 | FBP1 (0.65) | FBP1GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5395838-A | Aromatic aminomethyl substitutes compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-03-07 | — | — | US | disclosed |
| US-5252573-A | Quinazoline derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-10-12 | — | — | US | disclosed |
| US-5089499-A | Anticarcinogenic agents; thymidylate synthetase inhibitors; antiallergens; psoriasis | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-02-18 | — | — | US | disclosed |