Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9823907 | 0.78 | TSHR (0.41) | TSHRNPSR1 | |
| SCHEMBL14660479 | 0.75 | TSHR (0.52) | TSHRNPSR1LMNA | |
| SCHEMBL9252966 | 0.74 | TSHR (0.41) | TSHRNPSR1 | |
| SCHEMBL9011515 | 0.72 | TSHR (0.69) | TSHRNPSR1LMNA | |
| SCHEMBL1566072 | 0.72 | TSHR (0.69) | TSHRNPSR1LMNA | |
| SCHEMBL22914872 | 0.71 | GAA (0.43) | BACE1ATMGAAL3MBTL1LMNA | |
| SCHEMBL22015030 | 0.69 | GAA (0.48) | TSHRBACE1ATMGAAL3MBTL1 | |
| SCHEMBL9824399 | 0.68 | TSHR (0.57) | TSHRNPSR1LMNA | |
| SCHEMBL9823939 | 0.68 | TSHR (0.57) | TSHRNPSR1LMNA | |
| SCHEMBL9824431 | 0.68 | TSHR (0.57) | TSHRNPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391740-A | Monitoring therapeutic drug concentration in serum and plasma | ABBOTT LABORATORIES (US) | 1995-02-21 | — | — | US | disclosed |
| US-4952691-A | FOR BODY FLUIDS | ABBOTT LABORATORIES (US) | 1990-08-28 | — | — | US | disclosed |
| US-4585862-A | MEDICAL DIAGNOSIS | ABBOTT LABORATORIES (US) | 1986-04-29 | — | — | US | disclosed |