Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9251968 | 0.74 | TSHR (0.50) | TSHRNPSR1 | |
| SCHEMBL1073769 | 0.69 | CTSB (0.52) | NPSR1CTSB | |
| SCHEMBL29800774 | 0.69 | CTSB (0.52) | NPSR1CTSB | |
| SCHEMBL4446851 | 0.68 | CTSB (0.40) | CTSB | |
| SCHEMBL11254980 | 0.66 | ALDH1A1 (0.38) | TSHRCTSB | |
| SCHEMBL8557614 | 0.66 | PTGES2 (0.37) | CTSB | |
| SCHEMBL998791 | 0.66 | LIPG (0.41) | CTSB | |
| SCHEMBL28416490 | 0.65 | CTSB (0.47) | CTSB | |
| SCHEMBL9475157 | 0.65 | TDP1 (0.37) | CTSB | |
| SCHEMBL3431364 | 0.64 | CTSB (0.33) | CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391740-A | Monitoring therapeutic drug concentration in serum and plasma | ABBOTT LABORATORIES (US) | 1995-02-21 | — | — | US | disclosed |
| US-4952691-A | FOR BODY FLUIDS | ABBOTT LABORATORIES (US) | 1990-08-28 | — | — | US | disclosed |
| US-4585862-A | MEDICAL DIAGNOSIS | ABBOTT LABORATORIES (US) | 1986-04-29 | — | — | US | disclosed |