Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9252504 | 0.76 | SMN1; SMN2 (0.42) | SMN1; SMN2MAPTGAASLC6A3ALDH1A1 | |
| SCHEMBL8846872 | 0.73 | SMN1; SMN2 (0.53) | SMN1; SMN2MAPTGAASLC6A3ALDH1A1 | |
| SCHEMBL8846878 | 0.73 | SMN1; SMN2 (0.53) | SMN1; SMN2MAPTGAASLC6A3ALDH1A1 | |
| SCHEMBL6555228 | 0.73 | SMN1; SMN2 (0.53) | SMN1; SMN2MAPTGAASLC6A3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8993466 | 0.72 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTGAASLC6A3ALDH1A1 | |
| SCHEMBL12474357 | 0.65 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTGAASLC6A3ALDH1A1 | |
| SCHEMBL11543269 | 0.65 | CYP2D6 (0.42) | MAPTGAASLC6A3ALDH1A1MEN1 | |
| SCHEMBL8993503 | 0.64 | ALDH1A1 (0.47) | MAPTGAAALDH1A1DDB1CRBN | |
| SCHEMBL10843954 | 0.61 | SMN1; SMN2 (0.65) | SMN1; SMN2MAPTGAASLC6A3ALDH1A1 | |
| SCHEMBL9519015 | 0.61 | LMNA (0.40) | SMN1; SMN2MAPTGAAALDH1A1DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5574169-A | CHOLECYSTOKININ ANTAGONIST | ELI LILLY AND COMPANY (US) | 1996-11-12 | — | — | US | disclosed |
| US-5399708-A | Cholecystokinin and gastrin antagonists; gastrointestinal and central nervous system disorders | ELI LILLY AND COMPANY (US) | 1995-03-21 | — | — | US | disclosed |