Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | ACHE | P22303 | 17/20 | 0.57 |
| ▸ | BCHE | P06276 | 13/20 | 0.57 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 8/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9254247 | 0.89 | MAPT (0.52) | MAPTACHEBCHEGRIN1GRIN2A | |
| SCHEMBL29817788 | 0.86 | BCHE (0.79) | MAPTACHEBCHE | |
| SCHEMBL9256916 | 0.86 | ACHE (0.75) | ACHEBCHEGRIN1GRIN2ACHRM1 | |
| SCHEMBL29817915 | 0.83 | BCHE (0.77) | ACHEBCHE | |
| SCHEMBL9260660 | 0.83 | ACHE (0.54) | ACHEBCHEGRIN1GRIN2APOLB | |
| SCHEMBL2126156 | 0.80 | ACHE (0.74) | MAPTACHEBCHEGRIN1GRIN2A | |
| SCHEMBL10696947 | 0.80 | ACHE (0.61) | MAPTACHEBCHEPOLBGAA | |
| SCHEMBL18065461 | 0.79 | ACHE (0.73) | MAPTACHEBCHEGRIN1GRIN2A | |
| SCHEMBL9253566 | 0.78 | ACHE (0.64) | ACHEBCHETSHR | |
| SCHEMBL30356238 | 0.78 | ACHE (0.73) | MAPTACHEBCHEGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391553-A | Increasing cholinergic functionin mammals | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-02-21 | — | — | US | disclosed |