Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 11/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | BACE1 | P56817 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9249591 | 0.91 | ACHE (0.75) | ACHECYP1A2BCHECYP3A4BACE1 | |
| SCHEMBL10696834 | 0.89 | ACHE (0.62) | ACHECYP1A2BCHECYP3A4BACE1 | |
| SCHEMBL10696947 | 0.86 | ACHE (0.61) | ACHECYP1A2TSHRBCHEMEN1 | |
| SCHEMBL9257216 | 0.83 | ACHE (0.76) | ACHECYP1A2BCHECYP3A4BACE1 | |
| SCHEMBL9258030 | 0.81 | ACHE (0.68) | ACHECYP1A2TSHRBCHE | |
| SCHEMBL9259460 | 0.80 | ACHE (0.71) | ACHEBCHE | |
| SCHEMBL9252701 | 0.78 | MAPT (0.63) | ACHETSHRBCHE | |
| SCHEMBL9259739 | 0.77 | ACHE (0.72) | ACHEMEN1HTTKMT2A | |
| SCHEMBL9250740 | 0.76 | ACHE (0.53) | ACHEBCHEHTT | |
| SCHEMBL9256916 | 0.76 | ACHE (0.75) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391553-A | Increasing cholinergic functionin mammals | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-02-21 | — | — | US | disclosed |