Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 10/20 | 0.41 |
| ▸ | PRSS12 | P56730 | 2/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
| ▸ | PROC | P04070 | 1/20 | 0.39 |
| ▸ | HPN | P05981 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.39 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9247807 | 0.92 | ITGB3 (0.41) | ITGB3ITGA2BHDAC1HDAC8HDAC6 | |
| SCHEMBL9256882 | 0.91 | CHEK2 (0.38) | ITGB3ITGA2BHDAC1HDAC8HDAC6 | |
| SCHEMBL9252280 | 0.88 | ITGB3 (0.45) | ITGB3ITGA2BHDAC1HDAC8HDAC6 | |
| SCHEMBL9254520 | 0.87 | ITGB3 (0.44) | ITGB3ITGA2BHDAC1HDAC8HDAC6 | |
| SCHEMBL9247795 | 0.87 | ITGB3 (0.44) | ITGB3ITGA2BHDAC1HDAC8HDAC6 | |
| SCHEMBL9249022 | 0.86 | ITGB3 (0.44) | ITGB3ITGA2BHDAC1HDAC8HDAC6 | |
| SCHEMBL9252912 | 0.86 | ITGB3 (0.43) | ITGB3ITGA2BHDAC1HDAC8HDAC6 | |
| SCHEMBL9248824 | 0.85 | ITGB3 (0.42) | ITGB3ITGA2BHDAC1HDAC8HDAC6 | |
| SCHEMBL9252708 | 0.84 | CHEK2 (0.51) | ITGB3ITGA2BHDAC1HDAC8HDAC6 | |
| SCHEMBL9249490 | 0.84 | HDAC1 (0.56) | ITGB3ITGA2BHDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434150-A | Anticoagulants, cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1995-07-18 | — | — | US | disclosed |
| EP-0531883-A1 | Condensed 5-membered ring heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-03-17 | — | — | EP | disclosed |