SCHEMBL9253034

SCHEMBL9253034

C=Cc1cc(C)ccc1Cl

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
TDP1 Q9NUW8 4/20 0.40
TP53 P04637 2/20 0.40
LMNA P02545 3/20 0.38
GABRA1 P14867 2/20 0.38
GABRG2 P18507 2/20 0.38
GABRB3 P28472 2/20 0.38
HPGD P15428 2/20 0.38
CYP1A2 P05177 2/20 0.35
CYP2A6 P11509 2/20 0.35
MAPT P10636 3/20 0.34
POLB P06746 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
KDM4E B2RXH2 2/20 0.34
RAB9A P51151 2/20 0.34
RECQL P46063 1/20 0.34
MDM2 Q00987 1/20 0.34
GABRB2 P47870 1/20 0.34
MEN1 O00255 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL139560 0.82 GABRA1 (0.50) ALDH1A1TDP1TP53LMNAGABRA1
SCHEMBL9870633 0.79 TDP1 (0.43) ALDH1A1TDP1TP53HPGDCYP1A2
SCHEMBL5084622 0.78 TDP1 (0.44) ALDH1A1TDP1TP53LMNAHPGD
SCHEMBL16956792 0.77 GABRA1 (0.42) ALDH1A1TDP1TP53LMNAGABRA1
SCHEMBL7689361 0.77 ALDH1A1 (0.50) ALDH1A1TDP1LMNAGABRA1GABRG2
SCHEMBL29556567 0.76 ALDH1A1 (0.52) ALDH1A1TDP1TP53LMNAHPGD
SCHEMBL29392003 0.76 ALOX5 (0.47) ALDH1A1TDP1TP53LMNAHPGD
SCHEMBL87447 0.76 ALOX5 (0.47) ALDH1A1TDP1TP53LMNAHPGD
SCHEMBL820295 0.76 ALDH1A1 (0.52) ALDH1A1TDP1TP53LMNAHPGD
SCHEMBL13806116 0.76 LMNA (0.37) ALDH1A1TDP1LMNAGABRA1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4492784-A Adhesive for butadiene styrene copolymer PHILLIPS PETROLEUM COMPANY (US) 1985-01-08 US claimed
WO-2024073559-A1 BICYCLIC COMPOUNDS ALIGOS THERAPEUTICS, INC. (US) 2024-04-04 WO disclosed
US-9845374-B2 Mono vinyl aromatic conjugated diene block copolymer and polymer composition comprising said block copolymer and a mono vinylarene acrylate copolymer INEOS STYROLUTION GROUP GMBH (DE) 2017-12-19 US disclosed
EP-3019542-B1 MONO VINYL AROMATIC CONJUGATED DIENE BLOCK COPOLYMER AND POLYMER COMPOSITION COMPRISING SAID BLOCK COPOLYMER AND A MONO VINYLARENE ACRYLATE COPOLYMER INEOS STYROLUTION GROUP GMBH (DE) 2017-07-05 EP disclosed
US-20160168303-A1 MONO VINYL AROMATIC CONJUGATED DIENE BLOCK COPOLYMER AND POLYMER COMPOSITION COMPRISING SAID BLOCK COPOLYMER AND A MONO VINYLARENE ACRYLATE COPOLYMER INEOS STYROLUTION GROUP GMBH (DE) 2016-06-16 US disclosed
EP-3019542-A1 MONO VINYL AROMATIC CONJUGATED DIENE BLOCK COPOLYMER AND POLYMER COMPOSITION COMPRISING SAID BLOCK COPOLYMER AND A MONO VINYLARENE ACRYLATE COPOLYMER Styrolution Group GmbH (DE) 2016-05-18 EP disclosed
EP-2900645-A1 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION Bayer CropScience AG (DE) 2015-08-05 EP disclosed
WO-2015004043-A1 MONO VINYL AROMATIC CONJUGATED DIENE BLOCK COPOLYMER AND POLYMER COMPOSITION COMPRISING SAID BLOCK COPOLYMER AND A MONO VINYLARENE ACRYLATE COPOLYMER STYROLUTION GROUP GMBH (DE) 2015-01-15 WO disclosed
CN-101899270-B Sealing tape for ink jet recording head and ink jet recording head using same CANON KK 2013-11-27 CN disclosed
CN-101490142-B Use of composite materials based on carbon nanotubes as thickening agents for aqueous solutions ARKEMA FRANCE 2013-06-19 CN disclosed
EP-0326124-B1 A thermoplastic laminated film TOYO BOSEKI (JP) 1994-04-06 EP disclosed
EP-0348906-B1 HEAT-RESISTANT RESIN COMPOSITION SHOWA DENKO KABUSHIKI KAISHA (JP) 1992-10-07 EP disclosed
US-5073455-A Organic boron polymer with or without polyvinyl alcohol and a film-forming polymers, adhesion to hydrophobic and hydrophilic polymers and inorganic substrates TOYO BOSEKI KABUSHIKI KAISHA (JP) 1991-12-17 US disclosed
US-4994515-A Resin of styrene and unsaturated imide, high impact thermoplastic, bromine-containing reaction product, silicon resin or compound SHOWA DENKO KABUSHIKI KAISHA (JP) 1991-02-19 US disclosed
EP-0348906-A1 Heat-resistant resin composition SHOWA DENKO KABUSHIKI KAISHA (JP) 1990-01-03 EP disclosed
EP-0326124-A2 A thermoplastic laminated film Toyo Boseki Kabushiki Kaisha (JP) 1989-08-02 EP disclosed
US-4524180-A Rubber-modified, impact-resistant polymeric compositions THE DOW CHEMICAL COMPANY (US) 1985-06-18 US disclosed
US-4492784-A Adhesive for butadiene styrene copolymer PHILLIPS PETROLEUM COMPANY (US) 1985-01-08 US disclosed
US-4386190-A HIGH IMPACT RESISTANCE PHILLIPS PETROLEUM COMPANY (US) 1983-05-31 US disclosed
US-4379884-A FUNGUS, CHAETOMIUM BIOMASS PHILLIPS PETROLEUM COMPANY (US) 1983-04-12 US disclosed