Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 5/20 | 0.60 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.59 |
| ▸ | CYP2J2 | P51589 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5729030 | 0.97 | HRH1 (0.62) | HRH1P2RX7KCNH2CYP2J2HTR1A | |
| SCHEMBL10479167 | 0.92 | HRH1 (0.58) | HRH1P2RX7KCNH2CYP2J2 | |
| SCHEMBL7219639 | 0.85 | HTR1A (0.55) | HRH1ALDH1A1HTR1ADRD2 | |
| SCHEMBL9252798 | 0.83 | HRH1 (0.48) | HRH1KCNH2CYP2J2ALDH1A1 | |
| SCHEMBL9786914 | 0.80 | HRH1 (0.66) | HRH1KCNH2CYP2J2 | |
| SCHEMBL5113354 | 0.80 | HTR1A (0.61) | HRH1ALDH1A1HTR1ADRD2 | |
| SCHEMBL5694766 | 0.79 | HRH1 (0.68) | HRH1KCNH2CYP2J2 | |
| SCHEMBL16291199 | 0.79 | KCNH2 (0.67) | HRH1KCNH2CYP2J2HTR1ADRD2 | |
| SCHEMBL6619451 | 0.79 | HRH1 (0.64) | HRH1KCNH2CYP2J2HTR1ADRD2 | |
| SCHEMBL29459507 | 0.78 | HTR1A (0.62) | HRH1ALDH1A1HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |