Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 3/20 | 0.48 |
| ▸ | CYP2J2 | P51589 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10479167 | 0.90 | HRH1 (0.58) | HRH1CYP2J2KCNH2HTTRECQL | |
| SCHEMBL9253176 | 0.83 | HRH1 (0.60) | HRH1CYP2J2ALDH1A1KCNH2 | |
| SCHEMBL5729030 | 0.83 | HRH1 (0.62) | HRH1CYP2J2KCNH2 | |
| SCHEMBL9786852 | 0.78 | CYP19A1 (0.50) | HRH1CYP2J2KCNH2 | |
| SCHEMBL9232521 | 0.77 | HTR2A (0.67) | KDM4ELMNA | |
| SCHEMBL9256393 | 0.77 | CYP19A1 (0.49) | HRH1KCNH2 | |
| SCHEMBL9786858 | 0.77 | CYP2J2 (0.58) | HRH1CYP2J2LMNAMAPTKCNH2 | |
| SCHEMBL5407596 | 0.77 | ACHE (0.53) | — | |
| SCHEMBL9786842 | 0.76 | CYP2J2 (0.51) | HRH1CYP2J2LMNAMAPTKCNH2 | |
| SCHEMBL9873355 | 0.75 | CYP2J2 (0.48) | HRH1CYP2J2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |