Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GNRHR | P30968 | 4/20 | 0.37 |
| ▸ | NOX4 | Q9NPH5 | 6/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CYBB | P04839 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9160543 | 0.86 | MIF (0.37) | GNRHRALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9251207 | 0.82 | P2RX3 (0.37) | GNRHRKDM4EMEN1KMT2A | |
| SCHEMBL9251582 | 0.79 | ADORA3 (0.37) | ALDH1A1MEN1KMT2A | |
| SCHEMBL9156137 | 0.78 | KMT2A (0.37) | GNRHRALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9248865 | 0.78 | GNRHR (0.41) | GRIN1GRIN2BGNRHRNOX4GABRA5 | |
| SCHEMBL9158524 | 0.77 | L3MBTL1 (0.34) | ALDH1A1MEN1KMT2A | |
| SCHEMBL9249911 | 0.75 | CASR (0.35) | ALDH1A1KDM4EPKMCYP3A4 | |
| SCHEMBL9245510 | 0.74 | P2RX3 (0.40) | KDM4E | |
| SCHEMBL9243531 | 0.71 | ADORA3 (0.37) | ALDH1A1MEN1KMT2A | |
| SCHEMBL9249902 | 0.71 | KDM4E (0.33) | ALDH1A1KDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE34918-E | Antihistamines, muscle relaxants | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| US-5013736-A | 5-lipoxygenase inhibitors, smooth muscle relaxants | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1991-05-07 | — | — | US | disclosed |
| EP-0376223-A2 | Azaazulene derivative, process for preparing the same, and antiallergic agent and antiinflammatory agent containing the same | Kaken Pharmaceutical Co., Ltd. (JP) | 1990-07-04 | — | — | EP | disclosed |