Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MDM4 | O15151 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250230 | 0.89 | — | — | |
| SCHEMBL9249911 | 0.80 | CASR (0.35) | KDM4EMDM4ALDH1A1CA1CA2 | |
| SCHEMBL9160543 | 0.74 | MIF (0.37) | KDM4EALDH1A1MAPTHPGDALOX12 | |
| SCHEMBL9251207 | 0.74 | P2RX3 (0.37) | KDM4EMAPTPTGS1 | |
| SCHEMBL9158524 | 0.72 | L3MBTL1 (0.34) | ALDH1A1TDP1 | |
| SCHEMBL9251582 | 0.71 | ADORA3 (0.37) | ALDH1A1TP53MDM2SMN1; SMN2 | |
| SCHEMBL9253222 | 0.71 | GRIN1 (0.38) | KDM4EALDH1A1CYP3A4 | |
| SCHEMBL9159745 | 0.69 | HDAC4 (0.37) | KDM4EMDM4ALDH1A1CA1CA2 | |
| SCHEMBL9156137 | 0.68 | KMT2A (0.37) | KDM4EALDH1A1MAPTSMN1; SMN2TDP1 | |
| SCHEMBL9243990 | 0.68 | GNRHR (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE34918-E | Antihistamines, muscle relaxants | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| US-5013736-A | 5-lipoxygenase inhibitors, smooth muscle relaxants | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1991-05-07 | — | — | US | disclosed |
| EP-0376223-A2 | Azaazulene derivative, process for preparing the same, and antiallergic agent and antiinflammatory agent containing the same | Kaken Pharmaceutical Co., Ltd. (JP) | 1990-07-04 | — | — | EP | disclosed |