Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255598 | 0.83 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1MAPTNPC1 | |
| SCHEMBL9257131 | 0.79 | KDM4E (0.58) | ALDH1A1KMT2AMEN1LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL9876458 | 0.78 | KDM4E (0.57) | ALDH1A1KMT2AMEN1LMNAKDM4E | |
| SCHEMBL5396736 | 0.77 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1NPC1LMNA | |
| SCHEMBL19002660 | 0.73 | KMT2A (0.53) | KMT2AMEN1MAPTKDM4ETDP1 | |
| SCHEMBL19002662 | 0.73 | TP53 (0.50) | ALDH1A1KMT2ANPC1LMNAKDM4E | |
| SCHEMBL9829916 | 0.73 | ALDH1A1 (0.55) | ALDH1A1KMT2AMEN1MAPTNPC1 | |
| SCHEMBL10690642 | 0.72 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1MAPTNPC1 | |
| SCHEMBL16276134 | 0.70 | LMNA (0.63) | ALDH1A1NPC1LMNAPOLBCYP1A2 | |
| SCHEMBL9255037 | 0.70 | ALDH1A1 (0.59) | ALDH1A1KMT2AMEN1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446146-A | Treatment of liver disorders | NIPPON CHEMIPHAR CO., LTD. (JP) | 1995-08-29 | — | — | US | disclosed |
| EP-0326379-B1 | Therapeutic agent for liver disease and piperazine derivatives | NIPPON CHEMIPHAR CO (JP) | 1994-06-01 | — | — | EP | disclosed |
| US-5070089-A | INHIBITION OF LIPID PEROXIDATION | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |
| EP-0326379-A2 | Therapeutic agent for liver disease and piperazine derivatives | NIPPON CHEMIPHAR CO., LTD. (JP) | 1989-08-02 | — | — | EP | disclosed |