Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | DGKA | P23743 | 2/20 | 0.46 |
| ▸ | DGKG | P49619 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250144 | 0.91 | DRD2 (0.51) | HIF1AMAPTDGKADGKGDRD2 | |
| SCHEMBL9249824 | 0.84 | SETD7 (0.57) | OPRM1OPRK1OPRD1CYP2D6HTR7 | |
| SCHEMBL9379143 | 0.83 | MAPT (0.49) | HIF1AMAPTDGKADGKGDRD2 | |
| SCHEMBL9632595 | 0.81 | MAPT (0.48) | HIF1AMAPTDGKADGKGDRD2 | |
| SCHEMBL16481498 | 0.80 | OPRM1 (0.52) | HIF1AMAPTDGKADGKGDRD2 | |
| SCHEMBL8316991 | 0.80 | OPRM1 (0.52) | HIF1AMAPTDGKADGKGDRD2 | |
| SCHEMBL9252997 | 0.80 | SETD7 (0.56) | OPRM1OPRK1OPRD1CYP2D6SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9632502 | 0.80 | MAPT (0.47) | HIF1AMAPTDGKADGKGDRD2 | |
| SCHEMBL13904315 | 0.79 | HTR2A (0.61) | DRD2HTR2AHTR2BCYP3A4CYP2D6 | |
| SCHEMBL9382842 | 0.79 | HTR1A (0.65) | DRD2DRD4HTR2AHTR2CCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |