Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 2/20 | 0.46 |
| ▸ | EDNRA | P25101 | 2/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 5/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9252678 | 0.92 | ELANE (0.52) | EDNRBELANEMAPTPOLBNPSR1 | |
| SCHEMBL9257528 | 0.86 | ALDH1A1 (0.46) | ELANEMAPTPLA2G2AKDM4EMITF | |
| SCHEMBL9253426 | 0.85 | KDM4E (0.55) | ELANEMAPTKDM4EMITFALDH1A1 | |
| SCHEMBL9255291 | 0.79 | KMT2A (0.46) | MAPTPLA2G2AKDM4EMITFALDH1A1 | |
| SCHEMBL8389101 | 0.72 | DYRK1A (0.52) | EDNRBEDNRAELANEMAOBALDH1A1 | |
| SCHEMBL7676057 | 0.71 | LTB4R (0.67) | MAPTPOLBNPSR1PLA2G2ALTB4R | |
| SCHEMBL5471793 | 0.70 | KDM4E (0.61) | MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL9270434 | 0.70 | MEN1 (0.55) | EDNRBEDNRAMAPTPOLBNPSR1 | |
| SCHEMBL9259645 | 0.69 | MEN1 (0.65) | EDNRBEDNRAMAPTPOLBNPSR1 | |
| SCHEMBL7422868 | 0.69 | F10 (0.65) | EDNRBEDNRAPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382572-A | Viricides | SCHERING CORPORATION (US) | 1995-01-17 | — | — | US | disclosed |