Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | MARK4 | Q96L34 | 1/20 | 0.42 |
| ▸ | PNP | P00491 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257528 | 0.92 | ALDH1A1 (0.46) | KMT2ALMNAPLA2G2AMAPK8DHFR | |
| SCHEMBL9252678 | 0.82 | ELANE (0.52) | KMT2ALMNAPLA2G2AMAPTALDH1A1 | |
| SCHEMBL9255117 | 0.81 | RORA (0.47) | KMT2APLA2G2AALDH1A1KDM4EMEN1 | |
| SCHEMBL9253426 | 0.80 | KDM4E (0.55) | KMT2ALMNAMAPTALDH1A1KDM4E | |
| SCHEMBL9257319 | 0.79 | EDNRB (0.46) | LMNAPLA2G2AMAPTALDH1A1KDM4E | |
| SCHEMBL8359675 | 0.77 | KDM4E (0.56) | KMT2ALMNAPLA2G2AMAPK8MAPT | |
| SCHEMBL8355934 | 0.76 | KMT2A (0.51) | KMT2ALMNAMAPK8DHFRALDH1A1 | |
| SCHEMBL9257200 | 0.73 | RORA (0.47) | KMT2APLA2G2AMAPTALDH1A1KDM4E | |
| SCHEMBL9257233 | 0.71 | KDM4E (0.53) | KMT2ALMNAMAPTALDH1A1KDM4E | |
| SCHEMBL9740126 | 0.69 | KMT2A (0.56) | KMT2ALMNAPLA2G2AMAPK8MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382572-A | Viricides | SCHERING CORPORATION (US) | 1995-01-17 | — | — | US | disclosed |
| EP-0547145-A1 | ANTIVIRAL 2(1H)-QUINOLINONE COMPOUNDS | SCHERING CORPORATION (US) | 1993-06-23 | — | — | EP | disclosed |
| WO-1992004326-A1 | ANTIVIRAL COMPOUNDS | SCHERING CORPORATION (US) | 1992-03-19 | — | — | WO | disclosed |