Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | TDO2 | P48775 | 2/20 | 0.40 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.40 |
| ▸ | ACP3 | P15309 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253636 | 0.90 | OPRL1 (0.38) | IDO1TDO2IDO2OPRL1OPRM1 | |
| SCHEMBL4674804 | 0.82 | IDO1 (0.39) | IDO1OPRD1 | |
| SCHEMBL9253011 | 0.81 | IDO1 (0.39) | IDO1TDO2OPRL1OPRM1SLC6A2 | |
| SCHEMBL9668868 | 0.81 | ACP3 (0.38) | ACP3OPRL1OPRM1SLC6A2SLC6A4 | |
| SCHEMBL9253506 | 0.80 | IDO1 (0.41) | IDO1TDO2OPRL1OPRM1SLC6A2 | |
| SCHEMBL9251008 | 0.78 | IDO1 (0.43) | IDO1TDO2OPRL1OPRM1SLC6A2 | |
| SCHEMBL9257208 | 0.74 | IDO1 (0.51) | IDO1TDO2IDO2OPRM1SLC6A2 | |
| SCHEMBL9668878 | 0.73 | OPRD1 (0.40) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL9253016 | 0.73 | MRGPRX1 (0.40) | — | |
| SCHEMBL9253640 | 0.72 | SLC6A4 (0.40) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | claimed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | claimed |
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |