Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 13/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 11/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253500 | 0.90 | IDO1 (0.40) | OPRL1OPRM1OPRD1OPRK1IDO1 | |
| SCHEMBL9256092 | 0.78 | SLC6A2 (0.40) | OPRL1OPRM1OPRD1OPRK1ADRB2 | |
| SCHEMBL9257472 | 0.78 | MCOLN2 (0.36) | IDO1TDO2CYP2C9CYP3A4MAPT | |
| SCHEMBL9257877 | 0.75 | CA1 (0.40) | IDO1TDO2ADRA2ASLC6A2SLC6A4 | |
| SCHEMBL9252381 | 0.74 | IDO1 (0.41) | OPRL1OPRM1CYP2C19OPRD1OPRK1 | |
| SCHEMBL4674804 | 0.72 | IDO1 (0.39) | OPRD1CYP19A1IDO1L3MBTL1 | |
| SCHEMBL9253506 | 0.71 | IDO1 (0.41) | OPRL1OPRM1OPRD1OPRK1TSHR | |
| SCHEMBL9257208 | 0.69 | IDO1 (0.51) | OPRM1OPRD1OPRK1TSHRIDO1 | |
| SCHEMBL11681638 | 0.69 | OPRM1 (0.41) | OPRL1OPRM1CYP2C19OPRD1OPRK1 | |
| SCHEMBL9253640 | 0.69 | SLC6A4 (0.40) | CYP19A1ADRB2TSHRHIF1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |