Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 9/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257877 | 0.91 | CA1 (0.40) | IDO1TDO2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9668868 | 0.81 | ACP3 (0.38) | SLC6A2SLC6A4SLC6A3TACR1CHRM5 | |
| SCHEMBL9251016 | 0.80 | ALDH1A1 (0.44) | TACR1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL4674804 | 0.80 | IDO1 (0.39) | IDO1CYP19A1OPRD1 | |
| SCHEMBL9253500 | 0.78 | IDO1 (0.40) | IDO1TDO2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9253011 | 0.78 | IDO1 (0.39) | IDO1TDO2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9256621 | 0.77 | IDO1 (0.51) | IDO1TDO2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9668878 | 0.74 | OPRD1 (0.40) | TACR1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL9253016 | 0.74 | MRGPRX1 (0.40) | MRGPRX1TACR1 | |
| SCHEMBL8116971 | 0.73 | ALDH1A1 (0.40) | IDO1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |