Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253506 | 0.93 | IDO1 (0.41) | SLC6A4SLC6A2SLC6A3SMN1; SMN2TSHR | |
| SCHEMBL11231139 | 0.85 | ADRB2 (0.46) | SLC6A4SLC6A2SLC6A3ADRB2CYP19A1 | |
| SCHEMBL9256103 | 0.80 | CHRNA7 (0.34) | CYP19A1TDP1MGLLCHRM1 | |
| SCHEMBL9257480 | 0.80 | SLC6A3 (0.34) | SLC6A4SLC6A2SLC6A3TSHRCHRM1 | |
| SCHEMBL4674804 | 0.79 | IDO1 (0.39) | CYP19A1GAAMGLL | |
| SCHEMBL10528661 | 0.79 | SLC6A3 (0.54) | SLC6A4SLC6A2SLC6A3ADRB2HPGD | |
| SCHEMBL10460532 | 0.76 | SLC6A4 (0.55) | SLC6A4SLC6A2SLC6A3CYP19A1 | |
| SCHEMBL9257882 | 0.76 | ALDH1A1 (0.41) | SLC6A4SLC6A2SLC6A3GAATSHR | |
| SCHEMBL9668878 | 0.74 | OPRD1 (0.40) | GAASMN1; SMN2MGLLLMNA | |
| SCHEMBL9253016 | 0.74 | MRGPRX1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |