Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | DGKA | P23743 | 1/20 | 0.50 |
| ▸ | DGKG | P49619 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253169 | 0.93 | MAPT (0.54) | HTR1AKDM4ELMNAMAPTDGKA | |
| SCHEMBL9257110 | 0.90 | HTR1A (0.59) | HTR1AHTR7DRD3MAOBDRD2 | |
| SCHEMBL9256672 | 0.87 | HTR1A (0.59) | HTR1AHTR7DRD3MAOBDRD2 | |
| SCHEMBL9252146 | 0.82 | HTR1A (0.56) | HTR1AHTR7 | |
| SCHEMBL10836350 | 0.81 | ALDH1A1 (0.60) | HTR1AKDM4ELMNAMAPK1MAOB | |
| SCHEMBL9253664 | 0.78 | HTR1A (0.49) | HTR1AHTR7DRD3MAOBDRD2 | |
| SCHEMBL8316991 | 0.77 | OPRM1 (0.52) | KDM4ELMNAMAPTDGKADGKG | |
| SCHEMBL16481498 | 0.77 | OPRM1 (0.52) | KDM4ELMNAMAPTDGKADGKG | |
| SCHEMBL9231709 | 0.77 | HTR1A (0.80) | HTR1AKDM4ELMNAMAPK1DRD3 | |
| SCHEMBL13469510 | 0.77 | HTR1A (0.79) | HTR1ADRD3MAOBDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |