Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.59 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 2/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9256672 | 0.97 | HTR1A (0.59) | HTR1AP2RX7DRD3HTR7MAOB | |
| SCHEMBL9252146 | 0.92 | HTR1A (0.56) | HTR1AP2RX7HTR7OPRM1OPRD1 | |
| SCHEMBL9253620 | 0.90 | HTR1A (0.51) | HTR1ADRD3HTR7MAOBDRD2 | |
| SCHEMBL9253664 | 0.87 | HTR1A (0.49) | HTR1AP2RX7DRD3HTR7MAOB | |
| SCHEMBL9253169 | 0.82 | MAPT (0.54) | HTR1A | |
| SCHEMBL13469510 | 0.81 | HTR1A (0.79) | HTR1ADRD3MAOBDRD2 | |
| SCHEMBL7972938 | 0.78 | ALDH1A1 (0.70) | HTR1AMAOBDRD2 | |
| SCHEMBL1569172 | 0.78 | HTR1A (0.69) | HTR1ADRD3MAOBDRD2 | |
| SCHEMBL14028451 | 0.77 | HTR1A (0.79) | HTR1ADRD3MAOBDRD2 | |
| SCHEMBL14282966 | 0.77 | OPRD1 (0.60) | HTR1AP2RX7DRD3HTR7DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |