Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.62 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.62 |
| ▸ | ICMT | O60725 | 2/20 | 0.51 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11310471 | 0.88 | OPRM1 (0.58) | OPRM1OPRD1ICMTHPGDSOPRK1 | |
| SCHEMBL10600565 | 0.86 | OPRD1 (0.62) | OPRM1OPRD1ICMTOPRK1RAB9A | |
| SCHEMBL2457390 | 0.80 | OPRD1 (0.61) | OPRM1OPRD1OPRK1CYP2D6LMNA | |
| Bromide SCHEMBL10598951 | 0.79 | OPRD1 (0.59) | OPRM1OPRD1OPRK1CYP2D6LMNA | |
| Hydrochloric Acid SCHEMBL7647391 | 0.79 | OPRD1 (0.59) | OPRM1OPRD1OPRK1CYP2D6LMNA | |
| SCHEMBL4932269 | 0.78 | OPRD1 (1.00) | OPRM1OPRD1OPRK1KCNH2 | |
| SCHEMBL8366194 | 0.74 | HPGD (0.44) | OPRM1OPRD1ICMTHPGDSRAB9A | |
| SCHEMBL9434960 | 0.73 | OPRD1 (0.57) | OPRM1OPRD1OPRK1CYP2D6LMNA | |
| SCHEMBL8314711 | 0.71 | OPRD1 (0.58) | OPRM1OPRD1OPRK1CYP2D6LMNA | |
| SCHEMBL8316576 | 0.71 | OPRD1 (0.60) | OPRM1OPRD1OPRK1RAB9ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |