Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | STAT1 | P42224 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | NQO1 | P15559 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9156668 | 0.99 | KDM4E (0.47) | KDM4EALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL9253882 | 0.89 | ALDH1A1 (0.51) | KDM4EALDH1A1NPC1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL9157732 | 0.88 | ALDH1A1 (0.50) | KDM4EALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL9162577 | 0.80 | MTNR1A (0.56) | — | |
| SCHEMBL9246324 | 0.80 | KDM4E (0.49) | KDM4EALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL7795159 | 0.73 | MAOB (0.58) | KDM4EALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL29699265 | 0.73 | KDM4E (0.60) | KDM4EALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL18766190 | 0.73 | KDM4E (0.60) | KDM4EALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL18397897 | 0.71 | PPARG (0.65) | KDM4EALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL12228491 | 0.71 | CYP19A1 (0.60) | KDM4EALDH1A1NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5386034-A | Treatment of sleeping, psychological and nervous system disorders; anxiolytic agents, ovulation regulators | ADIR ET COMPAGNIE (FR) | 1995-01-31 | — | — | US | disclosed |
| US-5322849-A | Treating sleep disorders | ADIR ET COMPAGNIE (FR) | 1994-06-21 | — | — | US | disclosed |
| US-5300507-A | Treating sleep disorders | ADIR ET COMPAGNIE (FR) | 1994-04-05 | — | — | US | disclosed |
| US-5240919-A | Treating sleep disorders | ADIR ET COMPAGNIE (FR) | 1993-08-31 | — | — | US | disclosed |