Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL153672 | 0.84 | ALDH1A1 (0.56) | CSNK2A1ALDH1A1KMT2APOLBKDM4E | |
| SCHEMBL11419938 | 0.77 | ESR1 (0.55) | ESR1KDM4EHIF1APKMTSHR | |
| SCHEMBL3420916 | 0.77 | TLR8 (0.39) | CSNK2A1ALDH1A1KMT2APOLBMEN1 | |
| SCHEMBL27899857 | 0.77 | CSNK2A1 (0.38) | CSNK2A1ALDH1A1KMT2APOLBMEN1 | |
| Methane SCHEMBL7107717 | 0.76 | ALPG (0.38) | CSNK2A1ALDH1A1KMT2APOLBMEN1 | |
| SCHEMBL444097 | 0.76 | SMN1; SMN2 (0.54) | CSNK2A1ALDH1A1HIF1APDE4APDE4B | |
| SCHEMBL2556109 | 0.76 | CSNK2A1 (0.37) | CSNK2A1ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL25723968 | 0.76 | CSNK2A1 (0.37) | CSNK2A1ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL15956713 | 0.75 | ESR1 (0.56) | CSNK2A1ESR1HIF1ATSHR | |
| SCHEMBL718394 | 0.74 | KCNH2 (0.39) | CSNK2A1ALDH1A1KMT2APOLBPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5399705-A | 1,1'-bis(3-aminopropyl)-2,2'-diimidazole | BASF AKTIENGESELLSCHAFT (DE) | 1995-03-21 | — | — | US | disclosed |
| EP-0538680-B1 | 1,1'-bis-(3-aminopropyl)-2,2'-diimidazole | BASF AG (DE) | 1994-09-21 | — | — | EP | disclosed |
| EP-0538680-A2 | 1,1'-bis-(3-aminopropyl)-2,2'-diimidazole | BASF Aktiengesellschaft (DE) | 1993-04-28 | — | — | EP | disclosed |