Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9259438 | 0.96 | THRB (0.47) | THRBTHRANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8148796 | 0.86 | ACACB (0.46) | THRBTHRANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9251073 | 0.85 | HSD17B10 (0.50) | THRBTHRAKMT2AL3MBTL1 | |
| SCHEMBL8158421 | 0.83 | ACACB (0.44) | THRBKMT2AL3MBTL1ACACBLMNA | |
| SCHEMBL9252643 | 0.82 | RARB (0.56) | NPC1RAB9ASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL9256282 | 0.81 | HSD17B10 (0.49) | THRBTHRAKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL9259723 | 0.80 | ESR1 (0.51) | SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL9261995 | 0.80 | THRB (0.44) | THRBTHRASMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL1415501 | 0.79 | THRB (0.61) | THRBTHRANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9257556 | 0.78 | SMN1; SMN2 (0.57) | THRBTHRANPC1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5385693-A | Having rapid response and low phase transition temperature | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-01-31 | — | — | US | disclosed |
| EP-0357372-B1 | Optically active ester derivatives, preparation process thereof, liquid crystal materials and a light switching element | SUMITOMO CHEMICAL CO (JP) | 1994-11-17 | — | — | EP | disclosed |
| US-5264151-A | Optically active ester derivatives, preparation process thereof, liquid crystal materials and a light switching element | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-11-23 | — | — | US | disclosed |
| US-5124070-A | High speed response | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-06-23 | — | — | US | disclosed |
| EP-0357372-A2 | Optically active ester derivatives, preparation process thereof, liquid crystal materials and a light switching element | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-03-07 | — | — | EP | disclosed |