Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.42 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 4/20 | 0.36 |
| ▸ | FNTB | P49356 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9263736 | 0.86 | MAPK1 (0.46) | MAPTGABBR2GABBR1CYP1A2CYP2D6 | |
| Methyl Alcohol SCHEMBL9267439 | 0.86 | ALDH1A1 (0.45) | CYP1A2CYP2D6ALDH1A1L3MBTL1 | |
| SCHEMBL9257796 | 0.84 | MAPT (0.54) | MAPTGABBR2GABBR1FNTAFNTB | |
| SCHEMBL9259169 | 0.83 | MAPT (0.44) | MAPTGABBR2GABBR1FNTAFNTB | |
| SCHEMBL7655013 | 0.80 | MAPT (0.55) | MAPTGABBR2GABBR1FNTAFNTB | |
| SCHEMBL9261597 | 0.75 | GABBR2 (0.51) | MAPTGABBR2GABBR1CYP1A2CYP2D6 | |
| SCHEMBL9264723 | 0.74 | TDP1 (0.46) | MAPTCYP2D6PKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL7491183 | 0.73 | CYP1A2 (0.47) | CYP1A2PKMALDH1A1POLB | |
| SCHEMBL9261314 | 0.72 | PTGIR (0.42) | MAPTGABBR2GABBR1FNTAFNTB | |
| SCHEMBL9263236 | 0.72 | CYP3A4 (0.42) | ALDH1A1MEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393875-A | Hypotensive, cardiotonic and antiischemic agents | HOFFMANN-LA ROCHE INC. (US) | 1995-02-28 | — | — | US | disclosed |