Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.39 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 4/20 | 0.39 |
| ▸ | FNTA | P49354 | 3/20 | 0.37 |
| ▸ | FNTB | P49356 | 3/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSH | P09668 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9263236 | 0.87 | CYP3A4 (0.42) | CTSLCTSSATMTSHRCYP3A4 | |
| SCHEMBL9257796 | 0.87 | MAPT (0.54) | MAPTGABBR2GABBR1FNTAFNTB | |
| Methyl Alcohol SCHEMBL9254484 | 0.83 | MAPT (0.45) | MAPTGABBR2GABBR1FNTAFNTB | |
| SCHEMBL9263736 | 0.82 | MAPK1 (0.46) | MAPTGABBR2GABBR1ATMTSHR | |
| SCHEMBL9259162 | 0.77 | ACE2 (0.43) | CYP1A2 | |
| SCHEMBL7655013 | 0.76 | MAPT (0.55) | MAPTGABBR2GABBR1FNTAFNTB | |
| SCHEMBL9263580 | 0.75 | MAPT (0.40) | MAPTCTSLCTSSLMNAMEN1 | |
| SCHEMBL9263230 | 0.75 | ACE2 (0.43) | CTSKCTSLCTSSCTSBATM | |
| SCHEMBL9261597 | 0.71 | GABBR2 (0.51) | MAPTGABBR2GABBR1ATMTSHR | |
| Methyl Alcohol SCHEMBL9267439 | 0.71 | ALDH1A1 (0.45) | CYP3A4LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393875-A | Hypotensive, cardiotonic and antiischemic agents | HOFFMANN-LA ROCHE INC. (US) | 1995-02-28 | — | — | US | disclosed |