Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.44 |
| ▸ | F10 | P00742 | 3/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | TMPRSS15 | P98073 | 6/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
| ▸ | F3 | P13726 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257414 | 0.89 | TMPRSS15 (0.39) | F10F2MEN1LMNAGAA | |
| SCHEMBL9254812 | 0.84 | ITGB3 (0.57) | ITGB3ITGA2BF10F2MEN1 | |
| SCHEMBL9254628 | 0.84 | ITGB3 (0.57) | ITGB3ITGA2BF10F2MEN1 | |
| SCHEMBL9251193 | 0.73 | MAPT (0.47) | ITGB3ITGA2BF10F2MEN1 | |
| SCHEMBL9568473 | 0.73 | MAPT (0.47) | ITGB3ITGA2BF10F2MEN1 | |
| Hydrochloric Acid SCHEMBL8988846 | 0.71 | ITGB3 (0.41) | ITGB3ITGA2BF10F2FFAR1 | |
| SCHEMBL9253224 | 0.70 | MAPT (0.47) | ITGB3ITGA2BMEN1LMNAGAA | |
| SCHEMBL7118598 | 0.69 | ITGB3 (0.74) | ITGB3ITGA2BF10F2FFAR1 | |
| SCHEMBL9257048 | 0.68 | ITGB3 (0.51) | ITGB3ITGA2BF10F2FFAR1 | |
| SCHEMBL7274553 | 0.68 | ITGB3 (0.57) | ITGB3ITGA2BF10F2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |