Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5720493 | 0.84 | TSHR (0.36) | CYP19A1TSHR | |
| SCHEMBL799552 | 0.78 | CYP19A1 (0.41) | HCAR2CYP19A1CHRNB2CHRNA4 | |
| SCHEMBL876019 | 0.78 | CYP19A1 (0.43) | HCAR2CYP19A1 | |
| Hydrochloric Acid SCHEMBL27566786 | 0.76 | CYP19A1 (0.42) | HCAR2CYP19A1 | |
| SCHEMBL8444734 | 0.75 | CYP19A1 (0.38) | HCAR2CYP19A1CHRNB2CHRNA4 | |
| SCHEMBL16755475 | 0.75 | CYP19A1 (0.38) | HCAR2CYP19A1CHRNB2CHRNA4 | |
| SCHEMBL30581493 | 0.75 | CYP11B2 (0.48) | HCAR2CYP19A1 | |
| SCHEMBL197638 | 0.74 | — | — | |
| SCHEMBL8765679 | 0.73 | APLNR (0.38) | TSHRCHRNB2CHRNA4 | |
| SCHEMBL28705022 | 0.73 | KDM4E (0.39) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0065358-B1 | PRODUCTION OF 3-TRICHLOROMETHYL- AND 3-TRIFLUOROMETHYL-PYRIDINES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-05-28 | — | — | EP | claimed |
| EP-0144323-A1 | PRODUCTION OF POLYCHLORINATED PYRIDINE MIXTURES BY LIQUID PHASE CHLORINATION OF BETA-PICOLINE OR BETA-PICOLINE HYDROCHLORIDE | KALAMA CHEMICAL, INC. (US) | 1985-06-19 | — | — | EP | claimed |
| EP-0139648-A1 | PRODUCTION OF POLYCHLORINATED PYRIDINE MIXTURES BY LIQUID PHASE CHLORINATION OF BETA-PICOLINE OR BETA-PICOLINE HYDROCHLORIDE | KALAMA CHEMICAL, INC. (US) | 1985-05-08 | — | — | EP | claimed |
| US-4483993-A | MULTISTAGE CHLORINATION | KALAMA CHEMICAL, INC. (US) | 1984-11-20 | — | — | US | claimed |
| WO-1984004094-A1 | PRODUCTION OF POLYCHLORINATED PYRIDINE MIXTURES BY LIQUID PHASE CHLORINATION OF BETA-PICOLINE OR BETA-PICOLINE HYDROCHLORIDE | KALAMA CHEMICAL INC (US) | 1984-10-25 | — | — | WO | claimed |
| WO-1984004095-A1 | PRODUCTION OF POLYCHLORINATED PYRIDINE MIXTURES BY LIQUID PHASE CHLORINATION OF BETA-PICOLINE OR BETA-PICOLINE HYDROCHLORIDE | KALAMA CHEMICAL INC (US) | 1984-10-25 | — | — | WO | claimed |
| US-4429132-A | FROM 3-PICOLINE IN PRESENCE OF METAL OXIDE OR HALIDE CATALYST | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-01-31 | — | — | US | claimed |
| EP-0065358-A1 | Production of 3-trichloromethyl- and 3-trifluoromethyl-pyridines | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-11-24 | — | — | EP | claimed |
| CN-113527192-B | Preparation method of 2, 3-dichloro-5-trifluoromethyl pyridine | 武威广达科技有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-113248423-B | Preparation method of 2, 3-dichloro-5-trifluoromethyl pyridine | 武威广达科技有限公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-113527192-A | Preparation method of 2, 3-dichloro-5-trifluoromethylpyridine | 武威广达科技有限公司 | 2021-10-22 | — | — | CN | disclosed |
| CN-113248423-A | Preparation method of 2, 3-dichloro-5-trifluoromethylpyridine | 武威广达科技有限公司 | 2021-08-13 | — | — | CN | disclosed |
| US-10442765-B2 | Method for producing 2,3-dichloro-5-(trichloromethyl)pyridine | CHEMINOVA A/S (DK) | 2019-10-15 | — | — | US | disclosed |
| US-20180057459-A1 | METHOD FOR PRODUCING 2,3-DICHLORO-5-(TRICHLOROMETHYL)PYRIDINE | CHEMINOVA A/S (DK) | 2018-03-01 | — | — | US | disclosed |
| EP-0139648-A1 | PRODUCTION OF POLYCHLORINATED PYRIDINE MIXTURES BY LIQUID PHASE CHLORINATION OF BETA-PICOLINE OR BETA-PICOLINE HYDROCHLORIDE | KALAMA CHEMICAL, INC. (US) | 1985-05-08 | — | — | EP | disclosed |
| US-4483993-A | MULTISTAGE CHLORINATION | KALAMA CHEMICAL, INC. (US) | 1984-11-20 | — | — | US | disclosed |
| WO-1984004094-A1 | PRODUCTION OF POLYCHLORINATED PYRIDINE MIXTURES BY LIQUID PHASE CHLORINATION OF BETA-PICOLINE OR BETA-PICOLINE HYDROCHLORIDE | KALAMA CHEMICAL INC (US) | 1984-10-25 | — | — | WO | disclosed |
| WO-1984004095-A1 | PRODUCTION OF POLYCHLORINATED PYRIDINE MIXTURES BY LIQUID PHASE CHLORINATION OF BETA-PICOLINE OR BETA-PICOLINE HYDROCHLORIDE | KALAMA CHEMICAL INC (US) | 1984-10-25 | — | — | WO | disclosed |
| US-4429132-A | FROM 3-PICOLINE IN PRESENCE OF METAL OXIDE OR HALIDE CATALYST | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-01-31 | — | — | US | disclosed |
| EP-0065358-A1 | Production of 3-trichloromethyl- and 3-trifluoromethyl-pyridines | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-11-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180057459-A1 | METHOD FOR PRODUCING 2,3-DICHLORO-5-(TRICHLOROMETHYL)PYRIDINE | CBR3, USP5, CDC5L | HCAR2 3294/4885CYP19A1 3647/4885TSHR 4316/4885 |
| US-10442765-B2 | Method for producing 2,3-dichloro-5-(trichloromethyl)pyridine | CBR3, USP5, CDC5L | HCAR2 3294/4885CYP19A1 3647/4885TSHR 4316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.