Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5720493 | 0.82 | TSHR (0.36) | TSHR | |
| SCHEMBL13885073 | 0.77 | APLNR (0.35) | APLNRHSD17B1GABRA1GABRB2KDM4E | |
| SCHEMBL875313 | 0.76 | TAS2R14 (0.38) | APLNRCYP11B1CYP11B2CYP3A4 | |
| SCHEMBL8170002 | 0.76 | GABRA1 (0.54) | APLNRHSD17B1CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL9255050 | 0.73 | HCAR2 (0.40) | TSHRCHRNB2CHRNA4 | |
| SCHEMBL27314463 | 0.73 | GABRA1 (0.39) | APLNRHSD17B1CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL27314830 | 0.73 | GABRA1 (0.39) | APLNRHSD17B1CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL3819587 | 0.73 | — | — | |
| SCHEMBL28705022 | 0.71 | KDM4E (0.39) | KDM4ETSHR | |
| SCHEMBL29396834 | 0.71 | KDM4E (0.39) | KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778267-A1 | SULFONAMIDE DERIVATIVES AND INSECTICIDE, MITICIDE AND NEMATICIDE CONTAINING THE SAME | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-06-11 | — | — | EP | disclosed |