Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255731 | 0.92 | ALDH1A1 (0.38) | ALDH1A1KDM4EHPGDJMJD6MAPT | |
| SCHEMBL9247338 | 0.89 | MAPT (0.38) | ALDH1A1KDM4EHPGDJMJD6MAPT | |
| SCHEMBL9256887 | 0.84 | ALDH1A1 (0.37) | ALDH1A1KDM4EHPGDJMJD6DGAT1 | |
| SCHEMBL9253103 | 0.84 | ALOX5 (0.38) | ALDH1A1KDM4EHPGDMAPTTDP1 | |
| SCHEMBL9281623 | 0.81 | F10 (0.36) | MAPTL3MBTL1LMNANPC1RAB9A | |
| SCHEMBL9255100 | 0.80 | KDM4E (0.36) | ALDH1A1KDM4EHPGDDGAT1L3MBTL1 | |
| SCHEMBL9254434 | 0.80 | KDM4E (0.35) | ALDH1A1KDM4EHPGDL3MBTL1RAB9A | |
| SCHEMBL9257107 | 0.80 | F2 (0.37) | ALDH1A1HPGDGAARAB9ATSHR | |
| SCHEMBL9257668 | 0.80 | KDM4E (0.36) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL9254562 | 0.79 | PARP1 (0.34) | ALDH1A1KDM4EHPGDMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |