Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 2/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257668 | 0.90 | KDM4E (0.36) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL9247338 | 0.87 | MAPT (0.38) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL9255731 | 0.86 | ALDH1A1 (0.38) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL9255106 | 0.84 | ALDH1A1 (0.36) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL9255799 | 0.82 | F10 (0.41) | ALDH1A1MAPTNPC1RAB9ALMNA | |
| SCHEMBL9256883 | 0.81 | KDM4E (0.36) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL9253103 | 0.81 | ALOX5 (0.38) | ALDH1A1KDM4EHPGDMAPTF2 | |
| SCHEMBL9257625 | 0.79 | MAPT (0.33) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9257107 | 0.78 | F2 (0.37) | ALDH1A1HPGDRAB9AF2F10 | |
| SCHEMBL9254257 | 0.76 | HDAC1 (0.33) | ALDH1A1KDM4EHPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |