Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.53 |
| ▸ | HTR2B | P41595 | 3/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | MELK | Q14680 | 2/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.45 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.45 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.45 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.45 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.45 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.45 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.45 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.45 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10587731 | 0.86 | ALDH1A1 (0.55) | MELKALDH1A1 | |
| SCHEMBL3440731 | 0.83 | ALDH1A1 (0.69) | HTR2CHTR2BHTR2AMELKSLC2A1 | |
| SCHEMBL18585497 | 0.82 | ALDH1A1 (0.68) | ALDH1A1 | |
| SCHEMBL6582499 | 0.82 | ALDH1A1 (0.62) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7560518 | 0.81 | ALDH1A1 (0.67) | HTR2CHTR2BHTR2AMELKSLC2A1 | |
| SCHEMBL1790024 | 0.81 | NPC1 (0.56) | HTR2CHTR2BHTR2AMELKSLC2A1 | |
| SCHEMBL2732154 | 0.79 | MELK (0.58) | MELKSLC2A1 | |
| SCHEMBL8922280 | 0.79 | ALDH1A1 (0.47) | HTR2CHTR2BHTR2AALDH1A1DRD2 | |
| SCHEMBL4066466 | 0.77 | KDM4E (0.47) | HTR2CHTR2BHTR2AMELKSLC2A1 | |
| SCHEMBL12608360 | 0.77 | HTR2C (0.50) | HTR2CHTR2BHTR2AMELKSLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5455348-A | Anticoagulants | Thomae, Karl (DE) | 1995-10-03 | — | — | US | disclosed |