Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.49 |
| ▸ | WNT3A | P56704 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 7/20 | 0.48 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18585497 | 0.96 | ALDH1A1 (0.68) | ALDH1A1CTNNB1WNT3ARAB9ANPC1 | |
| SCHEMBL10587731 | 0.91 | ALDH1A1 (0.55) | ALDH1A1CTNNB1WNT3ARAB9ANPC1 | |
| SCHEMBL9338799 | 0.84 | ALDH1A1 (0.58) | ALDH1A1CTNNB1WNT3ARAB9ANPC1 | |
| SCHEMBL8922280 | 0.83 | ALDH1A1 (0.47) | ALDH1A1CTNNB1WNT3ARAB9ANPC1 | |
| SCHEMBL8384926 | 0.83 | ALDH1A1 (0.67) | ALDH1A1CTNNB1WNT3ARAB9ANPC1 | |
| SCHEMBL9255205 | 0.82 | HTR2C (0.53) | ALDH1A1 | |
| SCHEMBL29966888 | 0.81 | ALDH1A1 (0.92) | ALDH1A1CTNNB1WNT3ARAB9ANPC1 | |
| SCHEMBL1713977 | 0.81 | ALDH1A1 (0.92) | ALDH1A1CTNNB1WNT3ARAB9ANPC1 | |
| SCHEMBL23090398 | 0.79 | ALDH1A1 (0.88) | ALDH1A1CTNNB1WNT3ARAB9ANPC1 | |
| SCHEMBL15927492 | 0.79 | ALDH1A1 (0.88) | ALDH1A1CTNNB1WNT3ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151252-B | Iron death inhibitor-diarylamine acetamides | 维泰瑞隆有限公司 | 2024-08-27 | — | — | CN | disclosed |
| US-20240067597-A1 | ESTER COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2024-02-29 | — | — | US | disclosed |
| US-20240025838-A1 | ESTER COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2024-01-25 | — | — | US | disclosed |
| US-20240025838-A1 | ESTER COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2024-01-25 | — | — | US | disclosed |
| EP-4265593-A1 | ESTER COMPOUND | Mitsui Chemicals, Inc. (JP) | 2023-10-25 | — | — | EP | disclosed |
| CN-116635364-A | Ester compound | 三井化学株式会社 | 2023-08-22 | — | — | CN | disclosed |
| EP-4206182-A1 | ESTER COMPOUND | Mitsui Chemicals, Inc. (JP) | 2023-07-05 | — | — | EP | disclosed |
| US-20230159492-A1 | FERROPTOSIS INHIBITORS - DIARYLAMINE PARA-ACETAMIDES | Sironax Ltd. (KY) | 2023-05-25 | — | — | US | disclosed |
| CN-115151252-A | Iron death inhibitors diarylamine para-acetamides | 维泰瑞隆有限公司 | 2022-10-04 | — | — | CN | disclosed |
| WO-2022138635-A1 | ESTER COMPOUND | 三井化学株式会社 | 2022-06-30 | — | — | WO | disclosed |
| WO-2022045231-A1 | ESTER COMPOUND | 三井化学株式会社 | 2022-03-03 | — | — | WO | disclosed |
| WO-2013033310-A1 | MODULATORS OF REV-ERB | KAMENECKA THEODORE MARK (US) | 2013-03-07 | — | — | WO | disclosed |
| EP-0994876-B1 | QUATERNARY AMMONIUM COMPOUNDS AS TACHYKININ ANTAGONISTS | PFIZER LTD (GB) | 2004-09-08 | — | — | EP | disclosed |
| US-6380396-B1 | CHEMICAL INTERMEDIATES FOR ANTIINFLAMMATORY AGENTS | PFIZER INC. | 2002-04-30 | — | — | US | disclosed |
| US-6207678-B1 | USED FOR TREATING INFLAMMATORY DISEASE SUCH AS ARTHRITIS, PSORIASIS, ASTHMA OR INFLAMMATORY BOWEL DISEASE, CENTRAL NERVOUS SYSTEM DISORDER SUCH AS ANXIETY, DEPRESSION, DEMENTIA OR PSYCHOSIS, GASTROINTESTINAL DISORDERS | PFIZER INC | 2001-03-27 | — | — | US | disclosed |
| EP-0994876-A1 | QUATERNARY AMMONIUM COMPOUNDS AS TACHYKININ ANTAGONISTS | Pfizer Limited (GB) | 2000-04-26 | — | — | EP | disclosed |
| WO-1998057972-A1 | QUATERNARY AMMONIUM COMPOUNDS AS TACHYKININ ANTAGONISTS | PFIZER LIMITED (GB) | 1998-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240025838-A1 | ESTER COMPOUND | NR1H3, CYP4A11, H1-4 | ALDH1A1 650/4885CTNNB1 1461/4885WNT3A 1912/4885 |
| US-20240067597-A1 | ESTER COMPOUND | PPT1, GPER1, TCP1 | ALDH1A1 1965/4885CTNNB1 2935/4885WNT3A 3508/4885 |
| US-20230159492-A1 | FERROPTOSIS INHIBITORS - DIARYLAMINE PARA-ACETAMIDES | AIFM2, FECH, GPX4 | ALDH1A1 395/4885CTNNB1 3220/4885WNT3A 4650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.