Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9260997 | 0.87 | ESR1 (0.46) | LMNAL3MBTL1MAPTTP53RAB9A | |
| SCHEMBL9255747 | 0.84 | TP53 (0.40) | LMNAMAPTTP53HDAC8TSHR | |
| SCHEMBL9211054 | 0.82 | LMNA (0.44) | LMNAL3MBTL1MAPTTP53HDAC6 | |
| SCHEMBL9210655 | 0.82 | TP53 (0.39) | LMNAMAPTTP53ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL9219227 | 0.81 | TP53 (0.39) | LMNAMAPTTP53ALDH1A1HPGD | |
| SCHEMBL9256673 | 0.81 | TP53 (0.39) | LMNAMAPTTP53HDAC8NPC1 | |
| SCHEMBL9259987 | 0.80 | TP53 (0.50) | LMNAMAPTTP53HDAC8RAB9A | |
| SCHEMBL9255403 | 0.80 | MAPT (0.38) | LMNAL3MBTL1MAPTTP53HDAC8 | |
| SCHEMBL9213292 | 0.80 | MAPT (0.38) | LMNAMAPTTP53HDAC8NPC1 | |
| SCHEMBL9215578 | 0.79 | MAPT (0.37) | LMNAL3MBTL1MAPTTP53HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5475000-A | Antiulcer agents | CHINOIN GYOGYSZER-ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1995-12-12 | — | — | US | disclosed |