Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | MPO | P05164 | 2/20 | 0.48 |
| ▸ | XDH | P47989 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255011 | 0.90 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL9255516 | 0.86 | CTSV (0.56) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL5165208 | 0.85 | NQO2 (0.42) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL14773373 | 0.81 | CA12 (0.38) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL9258552 | 0.81 | KDM4E (0.47) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL13825521 | 0.80 | CA12 (0.41) | ALDH1A1KDM4EHPGDHSD17B10HTT | |
| SCHEMBL9264816 | 0.80 | CA12 (0.53) | LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL9257826 | 0.75 | FEN1 (0.55) | KDM4EKMT2AMPOXDH | |
| SCHEMBL9259823 | 0.75 | CA9 (0.55) | ALDH1A1HPGDLMNAKMT2AGAA | |
| SCHEMBL1660919 | 0.74 | CA12 (0.35) | ALDH1A1KDM4EHPGDHSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995019346-A1 | QUINAZOLINE-2,4-DIONES | SANDOZ LTD. (CH) | 1995-07-20 | — | — | WO | claimed |
| WO-1995019346-A1 | QUINAZOLINE-2,4-DIONES | SANDOZ LTD. (CH) | 1995-07-20 | — | — | WO | disclosed |