Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MASP2 | O00187 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 2/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | KLK8 | O60259 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255100 | 0.91 | KDM4E (0.36) | KDM4EHPGDMEN1GAAKMT2A | |
| SCHEMBL9247334 | 0.90 | PTGDR2 (0.40) | CASP1MASP2SMN1; SMN2PTGDR2KLK8 | |
| SCHEMBL9257842 | 0.89 | HRH3 (0.34) | HPGDGAAALDH1A1HDAC1L3MBTL1 | |
| SCHEMBL9253096 | 0.86 | TDP1 (0.40) | KDM4EHPGDMEN1GAAKMT2A | |
| SCHEMBL9256883 | 0.85 | KDM4E (0.36) | KDM4EHPGDMEN1GAAKMT2A | |
| SCHEMBL9256151 | 0.83 | HPGD (0.35) | HPGDNAMPTL3MBTL1 | |
| SCHEMBL9254497 | 0.82 | F2 (0.38) | GAAF2F10PLGMAPK1 | |
| SCHEMBL9257104 | 0.82 | HRH3 (0.39) | HPGDGAAALDH1A1HDAC1L3MBTL1 | |
| SCHEMBL9257665 | 0.81 | EDNRB (0.36) | KDM4EHPGDMEN1KMT2ACASP1 | |
| SCHEMBL9255731 | 0.79 | ALDH1A1 (0.38) | KDM4EHPGDMEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |