Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 2/20 | 0.32 |
| ▸ | NAMPT | P43490 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257842 | 0.92 | HRH3 (0.34) | HPGDTSHRHSD17B10HRH3NPC1 | |
| SCHEMBL9257104 | 0.90 | HRH3 (0.39) | HPGDTSHRHSD17B10HRH3TLR8 | |
| SCHEMBL9254248 | 0.86 | CASP1 (0.35) | HPGDTSHRHSD17B10HRH3NPC1 | |
| SCHEMBL9253893 | 0.85 | F10 (0.40) | TSHRHRH3TLR8CYP4F2CYP4A11 | |
| SCHEMBL9253096 | 0.83 | TDP1 (0.40) | HPGDNAMPTMAPT | |
| SCHEMBL9255728 | 0.83 | KDM4E (0.37) | HPGDNAMPTL3MBTL1 | |
| SCHEMBL9250731 | 0.83 | HRH3 (0.34) | HPGDTSHRHSD17B10HRH3NPC1 | |
| SCHEMBL9255100 | 0.81 | KDM4E (0.36) | HPGDNAMPTL3MBTL1 | |
| SCHEMBL9257434 | 0.80 | NPC1 (0.42) | HPGDTSHRHSD17B10HRH3TLR8 | |
| SCHEMBL9259034 | 0.80 | NPC1 (0.42) | HPGDTSHRHSD17B10HRH3TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |