Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MASP2 | O00187 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257665 | 0.89 | EDNRB (0.36) | KDM4EALDH1A1HPGDMASP2MEN1 | |
| SCHEMBL9247334 | 0.86 | PTGDR2 (0.40) | MASP2CASP1 | |
| SCHEMBL9255728 | 0.85 | KDM4E (0.37) | KDM4EALDH1A1HPGDMASP2MEN1 | |
| SCHEMBL9255799 | 0.84 | F10 (0.41) | ALDH1A1NPC1LMNAMAPTRAB9A | |
| SCHEMBL9255100 | 0.83 | KDM4E (0.36) | KDM4EALDH1A1HPGDMASP2MEN1 | |
| SCHEMBL9256887 | 0.81 | ALDH1A1 (0.37) | KDM4EALDH1A1HPGDNPC1LMNA | |
| SCHEMBL9253096 | 0.81 | TDP1 (0.40) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL9257621 | 0.79 | PDK1 (0.36) | MASP2MAP3K5 | |
| SCHEMBL9250731 | 0.79 | HRH3 (0.34) | ALDH1A1HPGDNPC1LMNAMAPT | |
| SCHEMBL9257104 | 0.79 | HRH3 (0.39) | ALDH1A1HPGDNPC1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |