Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | USP1 | O94782 | 1/20 | 0.36 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1548278 | 0.72 | ALDH1A1 (0.54) | ALDH1A1HPGDUSP1WDR48SMN1; SMN2 | |
| SCHEMBL1338840 | 0.72 | ALDH1A1 (0.47) | ALDH1A1HPGDUSP1WDR48SMN1; SMN2 | |
| SCHEMBL34460865 | 0.70 | GRM2 (0.42) | — | |
| SCHEMBL31158570 | 0.70 | GRM2 (0.42) | — | |
| SCHEMBL3476441 | 0.70 | NPC1 (0.38) | ALDH1A1NISCHNPC1 | |
| SCHEMBL31470946 | 0.68 | ALDH1A1 (0.40) | ALDH1A1HPGDSMN1; SMN2ATMNISCH | |
| SCHEMBL31470939 | 0.68 | ALDH1A1 (0.40) | ALDH1A1HPGDSMN1; SMN2ATMNISCH | |
| SCHEMBL9790532 | 0.67 | ALDH1A1 (0.42) | ALDH1A1HPGDUSP1WDR48LMNA | |
| SCHEMBL31470938 | 0.66 | MAOB (0.45) | ALDH1A1HPGDUSP1WDR48LMNA | |
| SCHEMBL3476376 | 0.66 | ALDH1A1 (0.41) | ALDH1A1HPGDUSP1WDR48LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382665-A | Synthesis of oxazolines and oxazines | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) | 1995-01-17 | — | — | US | disclosed |
| US-5382665-A | Synthesis of oxazolines and oxazines | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) | 1995-01-17 | — | — | US | disclosed |