Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.41 |
| ▸ | F2 | P00734 | 8/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250395 | 0.86 | F2 (0.42) | F2PRSS1RAB9AITGB3ITGA2B | |
| SCHEMBL9256883 | 0.84 | KDM4E (0.36) | NPC1RAB9AALDH1A1LMNATP53 | |
| SCHEMBL9257073 | 0.84 | F10 (0.39) | F10F2PRSS1F7NPC1 | |
| SCHEMBL9253893 | 0.83 | F10 (0.40) | F10F2PRSS1NPC1RAB9A | |
| SCHEMBL9257434 | 0.83 | NPC1 (0.42) | F10F2PRSS1NPC1RAB9A | |
| SCHEMBL9259034 | 0.83 | NPC1 (0.42) | F10F2PRSS1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL9256062 | 0.82 | NPC1 (0.41) | F10F2PRSS1NPC1RAB9A | |
| SCHEMBL9256887 | 0.82 | ALDH1A1 (0.37) | F10F2NPC1RAB9AALDH1A1 | |
| SCHEMBL9254497 | 0.82 | F2 (0.38) | F10F2PRSS1NPC1RAB9A | |
| SCHEMBL9288922 | 0.80 | TDP1 (0.43) | F10F2F7NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |