SCHEMBL6322871

SCHEMBL6322871

CCCOC(C=O)OCCc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSK P43235 2/20 0.46
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
HCAR2 Q8TDS4 1/20 0.38
SIGMAR1 Q99720 2/20 0.38
PTGES O14684 3/20 0.37
ALOX5 P09917 3/20 0.37
PPARG P37231 3/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
NPC1 O15118 1/20 0.37
MAPT P10636 1/20 0.37
NFKB1 P19838 1/20 0.37
RAB9A P51151 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
AKR1B10 O60218 1/20 0.36
AKR1B1 P15121 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
AKR1C3 P42330 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6322566 0.90 CTSK (0.43) CTSKCA1CA2CA9HCAR2
SCHEMBL531070 0.79 CA1 (0.39) CTSKCA1CA2CA9SIGMAR1
SCHEMBL8673814 0.78 CTSK (0.44) CTSKCA1CA2CA9HCAR2
SCHEMBL2215309 0.78 TSHR (0.32) SMN1; SMN2
SCHEMBL11705539 0.75 GPR52 (0.40) SMN1; SMN2
SCHEMBL11705544 0.75 GPR52 (0.40) SMN1; SMN2
SCHEMBL9256016 0.74 LMNA (0.45) CTSKCA1CA2CA9PTGES
SCHEMBL6268780 0.73 CA1 (0.44) CA1CA2CA9HCAR2PTGES
SCHEMBL23829512 0.72 SIGMAR1 (0.43) CTSKCA1CA2CA9HCAR2
SCHEMBL97918 0.71 MEN1 (0.42) CTSKCA1CA2CA9HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6844302-B1 Encapsulated flavor and fragrance INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2005-01-18 US claimed