Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7199605 | 0.94 | KDM4E (0.53) | KDM4EPOLBAPEX1RECQLTSHR | |
| SCHEMBL9412075 | 0.88 | KDM4E (0.53) | KDM4EPOLBAPEX1RECQLNPC1 | |
| SCHEMBL9255523 | 0.82 | CYP4F2 (0.47) | KDM4EPOLBAPEX1RECQLTSHR | |
| SCHEMBL9412114 | 0.82 | KDM4E (0.53) | KDM4EPOLBAPEX1RECQLNPC1 | |
| SCHEMBL16601605 | 0.81 | RAB9A (0.49) | POLBNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL11493699 | 0.79 | KDM4E (0.50) | KDM4EPOLBAPEX1RECQLTSHR | |
| SCHEMBL25370326 | 0.78 | CA2 (0.50) | KDM4EPOLBNPC1RAB9AMAPT | |
| SCHEMBL31238895 | 0.78 | CA2 (0.50) | KDM4EPOLBNPC1RAB9AMAPT | |
| SCHEMBL1546125 | 0.78 | KDM4E (0.51) | KDM4EPOLBAPEX1RECQLNPC1 | |
| SCHEMBL13341117 | 0.78 | PTGS1 (0.43) | POLBNPC1RAB9AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439909-A | 2-Substituted with amide or thioamide group; antioxidant for lipoproteins, antilipemic agents, anticholesterol agents | ADIR ET COMPAGNIE (FR) | 1995-08-08 | — | — | US | disclosed |
| US-5420132-A | Antilipemic agents | ADIR ET COMPAGNIE (FR) | 1995-05-30 | — | — | US | disclosed |
| EP-0624582-A1 | Substituted benzodioxine, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-11-17 | — | — | EP | disclosed |